COVID-19

Coronavirus disease (COVID-19)

A Setback for Remdesivir—and Sunlight

Remdesivir vial

Hopes for a promising COVID-19 treatment suffered a setback yesterday after WHO inadvertently published a summary of a remdesivir clinical trial on its website, STAT reports.

The summary, which has since been removed, showed the drug "failed to speed the improvement of patients with Covid-19 or prevent them from dying," according to STAT.

How the coronavirus is affecting the world

covid-19 pandemic

Dealing with the unforeseen challenges caused by the COVID-19 pandemic has taken a significant toll on people all across the world. Medical News Today has spoken with people from different countries, asking how the pandemic has impacted their lives.

At the time of writing this Special Feature, there are over 2,700,000 confirmed cases of COVID-19 across the globe.

According to official reports, the largest numbers of confirmed cases are in the United States, Italy, Spain, and France. However, even the countries that the new coronavirus has hit less aggressively are still under considerable strain.

Coronavirus drifts through the air in microscopic droplets – here’s the science of infectious aerosols

Pflugge droplets

During the 1970s when I was growing up in Southern California, the air was so polluted that I was regularly sent home from high school to “shelter in place.” There might not seem to be much in common between staying home due to air pollution and staying home to fight the coronavirus pandemic, but fundamentally, both have a lot to do with aerosols.

Aerosols are the tiny floating pieces of pollution that make up Los Angeles’ famous smog, the dust particles you see floating in a ray of sunshine and also the small droplets of liquid that escape your mouth when you talk, cough or breathe. These small pieces of floating liquids can contain pieces of the coronavirus and can be major contributor to its spread.

A french study finds that nicotine protects from COVID-19 disease

Nicotine patch

Does Nicotine Protect Against Covid? This is the very serious hypothesis of a Pitié-Salpêtrière team and a world renowned neurobiologist. It should soon be the subject of a clinical study: nicotinic patches will be administered to patients and caregivers to measure the effects.

Nicotine, a preventive and curative remedy against Covid, is therefore the hypothesis defended by an internal medicine team from the Pitié Salpétrière hospital, and a world-renowned neurobiologist, member of the Academy of Sciences, Jean-Pierre Changeux.

Bat survey identifies six new coronaviruses

Bats flying

Scientists have discovered six previously unknown coronaviruses in bats. The animals were in regions of Myanmar where humans come into close contact with wildlife as a result of agriculture, deforestation, and other ecological disruption.

Wild bats are generally beneficial for people living in many areas around the world. They pollinate crops, control pest insects, and produce guano, which farmers collect from caves to use as fertilizer.

Many experts think that these mammals were the original hosts of several viruses that pose a significant threat to human health.

Hydroxychloroquine is not such a good idea

Hydroxychloroquine as treatment for COVID-19

Humans have trouble grasping an essential fact about COVID-19: Nothing will be easy.

Once hailed as a wonder treatment, the antimalarial hydroxychloroquine is starting to look like not such a good idea.

New but not yet peer-reviewed research among 368 patients found the drug didn’t help patients and more patients who received it died than those who had standard care, AP reports.

SARS-CoV-2 may affect more children than scientists initially thought

Pediatrician

Researchers have estimated that the number of children in the United States who spent time in a hospital with COVID-19 is likely higher than officials had previously thought. And the projected numbers of severe cases in children may overtax the health system, they warn.

According to a study paper newly published in the Journal of Public Health Management & Practice, officials may have been underestimating the impact of SARS-CoV-2 on children.

Could an antiparasitic drug kill off SARS-CoV-2 within 2 days?

COVID 19 researchers

A new study in cell cultures suggests that ivermectin, an existing antiparasitic drug, is able to eliminate SARS-CoV-2 within 48 hours. However, whether this approach is safe and effective in human beings remains to be seen.

As the race toward an efficient treatment for coronavirus disease 19 (COVID-19) continues, researchers are experimenting with new and old drugs alike.

A study paper recently published in the journal Antiviral Research indicates that investigators from the Victorian Infectious Diseases Reference Laboratory (VIDRL) and Monash University, both in Melbourne, Australia, may have found a viable treatment: an existing antiparasitic drug called ivermectin.

Serology-based tests for COVID-19

COVID-19 tests

Serology testing for SARS-CoV-2 is at increased demand in order to better quantify the number of cases of COVID-19, including those that may be asymptomatic or have recovered. Serology tests are blood-based tests that can be used to identify whether people have been exposed to a particular pathogen by looking at their immune response. In contrast, the RT-PCR tests currently being used globally to diagnose cases of COVID-19 can only indicate the presence of viral material during infection and will not indicate if a person was infected and subsequently recovered. These tests can give greater detail into the prevalence of a disease in a population by identifying individuals who have developed antibodies to the virus.

COVID-19: What happens inside the body?

x-ray

How does the body respond when the SARS-CoV-2 virus infects it? Which physiological processes help or hinder us in getting rid of the virus, and which processes ensure that we have a mild form of COVID-19, the disease that the virus causes? In this Special Feature, we investigate.

The more we learn about COVID-19, the more we have to question our assumptions about it.

Early on in the COVID-19 pandemic, our information about the disease came from clinical case reports of COVID-19 and what we knew about influenza pandemics and the severe acute respiratory syndrome (SARS) resulting from SARS-CoV.

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