Treatment

Treatment explained

Treatment

Treatment against viral diseases have been a chimera until 1963. The discovery of antiviral drugs has always been an adaptable endeavour. The development of antiviral drugs is a very complex process., due to the elusive nature of the genetic material of viruses, being them DNA, RNA or retroviruses (such HIV).

Polio Vaccine—A Temporary Solution?

poliovaccine

Could existing polio vaccines be used to fight coronavirus?

Researchers—including Robert Gallo, who helped discover HIV—are seeking funding to test their theory, making their case in Science this week.

They argue that live attenuated vaccines can trigger "interferon and other innate immunity mechanisms" to provide protection against unrelated pathogens.

In theory, a live polio vaccine then could possibly buy the body time to develop the right antibodies against SARS-CoV-2, NBC reports.

Red Flags Raised on Research

red flags raised

Two top medical journals are reviewing major studies they published on potential COVID-19 treatments (including hydroxychloroquine) after questions about their data surfaced yesterday, Science reports.

The papers in The Lancet and the New England Journal of Medicine shared a common source: A little-known company called Surgisphere.

COVID-19: New drug candidates, treatments offer reasons for hope

new drug

Every 2 weeks, Medical News Today rounds up the latest research results that may offer hope among the turmoil that is the COVID-19 pandemic. In our previous Special Feature, we looked at vaccine trials and antibody tests.

In this article, we cover the latest scientific discoveries, from antibodies and testing to drug candidates and potential treatments.

The Problem with Propofol

Propofol

Demand for propofol—the ubiquitous intravenous anesthetic—has skyrocketed since the drug became key to ventilating ICU patients with COVID-19.

But hospitals have seen stressful shortages.

Why?

An investigation tracking propofol’s notoriously opaque journey from production to patient care underscores the vulnerabilities of a supply chain that relies on a few countries for production—and now faces a global crisis.

Scientists identify promising drug candidates for COVID-19

COVID-19 tests

By mapping interactions between human proteins and the new coronavirus, researchers have pinpointed 29 potential treatments using drugs already approved by the Food and Drug Administration (FDA) for a wide range of other conditions.

There is currently no vaccine or antiviral drug with proven efficacy against SARS-CoV-2, the virus that causes COVID-19, though several clinical trials are underway.

Lack of in-depth knowledge about how the newly emerged virus interacts with human cells has hampered the hunt for an effective treatment.

Remdesivir explained – what makes this drug work against viruses?

Remdesivir

With the FDA approving Gilead’s Remdesivir as an emergency use treatment for the most acute cases of COVID-19, many people are wondering what type of a drug it is.

Remdesivir is a member of one of the oldest and most important classes of drugs – known as nucleoside analogue. Currently there are more than 30 of these types of drugs that have been approved for use in treating viruses, cancers, parasites, as well as bacterial and fungal infections, with many more currently in clinical and preclinical trials.

New drug candidate against the novel coronavirus

COVID-19 treatment

A team of scientists from China has found a new candidate drug against the novel coronavirus, SARS-CoV-2, which works by inhibiting a key part of the virus’s machinery.

Much of the world is on hold until scientists find a vaccine for the novel coronavirus, which has, so far, claimed hundreds of thousands of lives.

However, with current estimates suggesting that a vaccine is 12–18 months away, many people are placing increasing hope on an effective treatment for COVID-19.

A french study finds that nicotine protects from COVID-19 disease

Nicotine patch

Does Nicotine Protect Against Covid? This is the very serious hypothesis of a Pitié-Salpêtrière team and a world renowned neurobiologist. It should soon be the subject of a clinical study: nicotinic patches will be administered to patients and caregivers to measure the effects.

Nicotine, a preventive and curative remedy against Covid, is therefore the hypothesis defended by an internal medicine team from the Pitié Salpétrière hospital, and a world-renowned neurobiologist, member of the Academy of Sciences, Jean-Pierre Changeux.

Hydroxychloroquine is not such a good idea

Hydroxychloroquine as treatment for COVID-19

Humans have trouble grasping an essential fact about COVID-19: Nothing will be easy.

Once hailed as a wonder treatment, the antimalarial hydroxychloroquine is starting to look like not such a good idea.

New but not yet peer-reviewed research among 368 patients found the drug didn’t help patients and more patients who received it died than those who had standard care, AP reports.

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